Production of bioethanol from leachate, a byproduct from landfills, has been seen to be a potential solution that minimizes dependence on non-renewable energy resources and the threatening issues associated with environmental pollution due to solid wastes. Municipal solid waste is partly composed of organic matter, which produces ethanol compounds through anaerobic fermentation based on the previous study. This research study, therefore, presents the idea of a comparative analysis of the ethanol yield of fermented leachate from the sampling sites of Basey and Ormoc City in the Philippines. The study used the experimental research design using three different amounts of Saccharomyces cerevisiae as formulation variants (150g, 200g, 250g) for both sampling sites. The production of the results showed that 7.045%, 9.39%, and 10.015%, then 6.88%, 7.615%, and 9.52% of average ethanol by volume from Ormoc City and Basey sampling sites, respectively. The result shows in the experiment that potential sugar content has a notable distinction for landfill sites but not the raw leachate. Results show that there is no interaction between the two factors. Moreover, there is a significant difference in the ethanol yield to the landfill sites and the concentration of Saccharomyces cerevisiae. In addition, results show that Ormoc sampling site has a better potential for bioethanol production than the Basey landfill. For further studies, the conduct of a comparative study on ethanol yield from leachate collected from different climates is highly encouraged, to further assess whether climate conditions, such as dry and wet seasons, directly affect potential ethanol yield.